Space shuttle Endeavour blasts off

Mission managers loaded the crew into the space shuttle Endeavour early Monday for a second attempt in as many days at getting into orbit.

Three Americans, including two from the International Security Assistance Force, have been killed in Afghanistan, the NATO-led force said Saturday.

Togo, which pulled out of the Africa Cup of Nations soccer competition after a terrorist attack on their team bus, have been suspended from taking part in the next two competitions.

French Culture Minister Frederic Mitterrand says he will not resign over his admission in a book that he paid to have sex with “boys” in Thailand.

A prison in northern Illinois is the leading contender to house detainees transferred from the federal facility in Guantanamo Bay, Cuba, a senior Obama administration official confirmed Saturday.

An explosion at a coal mine in northeastern China killed at least 42 workers early Saturday, state media reported.

Eighteen people were rescued — but as many as 21 others were missing — after a boat sank late Sunday in remote seas off Australia’s Cocos Islands, according to Australian Customs and Border Protection Service officials.

A suicide car bomber who blew himself up at a police checkpoint Saturday in Peshawar killed 11 people and wounded 26 — marking the second straight day of major violence in the area, authorities said.

When Amanda Knox’s parents head to Italy for closing arguments in their daughter’s murder trial, they’ll be carrying a present they desperately hope she can use: a plane ticket home.

Severe winter weather continued its stranglehold on Europe as travelers battled heavy snow, airlines canceled flights and motorists were left stranded.

With just over 12 percent of votes counted in Chile’s presidential election, conservative billionaire businessman Sebastian Pinera and former president Eduardo Frei appeared headed toward a runoff election.

More than 1 million babies born prematurely die each year before they are a month old, the March of Dimes says in the first comprehensive global report on premature births.

Iran has stepped up efforts to combat what it calls American “plots,” according to state media, with at least $20 million approved for a special committee to thwart such schemes.

A strong earthquake strikes Haiti, destroying houses and inflicting what its ambassador to the U.S. called a catastrophe for the Western Hemisphere’s poorest nation. How you can help

At least nine people were killed and at least 30 were wounded Friday in a suicide attack targeting Sunni Muslim worshipers at a mosque in northern Iraq, an Interior Ministry said.

A former speaker of the Rwandan parliament warned that his country could again descend into chaos and violence, 15 years after the genocide that killed as many as 1 million people.